Alcohol Inhibition of a Chemically-Activated GIRK2 Channel
نویسندگان
چکیده
منابع مشابه
Impermeability of the GIRK2 weaver channel to divalent cations.
A single amino acid mutation (G156S) in the putative pore-forming region of the G protein-sensitive, inwardly rectifying K(+) channel subunit, GIRK2, renders the conductance constitutively active and nonselective for monovalent cations. The mutant channel subunit (GIRK2wv) causes the pleiotropic weaver disease in mice, which is characterized by the selective vulnerability of cerebellar granule ...
متن کاملUniversal cements: dual activated and chemically activated
Objective: The aim of the present study was to assess the bond strength of universal cements cured either dually or chemically only. Methods: Three cements were assessed using different types of application: dual activated (DA) or chemically activated (CA). In total 80 dentin blocks were used, obtained through the enamel wear of the lingual and buccal surfaces of bovine incisors. Standard cone-...
متن کاملA Comparative Evaluation of Chemically Activated, Light-activated and Laser-activated Tooth Bleaching Systems
Background: Tooth bleaching systems can be classified as chemically activated, light-activated and laser-activated depending on activation mechanism. There is no unanimity of opinion with respect to the whitening efficacy and effect on enamel surface texture of these three types of systems. So, the present study was carried out to comparatively evaluate their whitening efficacy and effect on en...
متن کاملeffect of sub-grid scales on large eddy simulation of particle deposition in a turbulent channel flow
چکیده ندارد.
15 صفحه اولMembrane-delimited Inhibition of Maxi-K Channel Activity by the Intermediate Conductance Ca2+-activated K Channel
The complexity of mammalian physiology requires a diverse array of ion channel proteins. This diversity extends even to a single family of channels. For example, the family of Ca2+-activated K channels contains three structural subfamilies characterized by small, intermediate, and large single channel conductances. Many cells and tissues, including neurons, vascular smooth muscle, endothelial c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2015
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2014.11.2013